So a fast Gibbs sampling or parallel Gibbs sampling are absolutely rescues. There are two such papers recently, with published codes (that is great!):
PLDA: Parallel Latent Dirichlet Allocation for Large-scale Applications by Wang Yi et al at Google, code
here is a comment from LingPipe's blog:
Porteous et al. (2008) Fast Collapsed Gibbs Sampling for Latent Dirichlet AllocationAnother paper related to topic model inference in large scale corpus is